Jeurissen ME, Boerbooms AM, van de Putte LB, Kruijsen MW "Azathioprine induced fever, chills, rash, and hepatotoxicity in rheumatoid arthritis. RA for a year, strangely enough it was a year after i moved from Australia to live and work in Bali- Indonesia. As a result my diet changed. However, people with autoimmune disorders including rheumatoid arthritis, Crohn's disease, ankylosing spondylitis, and psoriasis may have a higher risk of lymphoma. Talk to your doctor about your individual risk. It's true that over time, about half of people with MS can have some cognitive problems. That means poor focus, slowed thinking, or a fuzzy memory. cost periactin medication periactin
Azathioprine may also be used for purposes not listed in this medication guide. How should I take azathioprine Imuran? Studies in pregnant women have demonstrated a risk to the fetus. However, the benefits of therapy in a life threatening situation or a serious disease, may outweigh the potential risk.
Using this medicine while you are pregnant can harm your unborn baby. Use an effective form of birth control to keep from getting pregnant. If you think you have become pregnant while using this medicine, tell your doctor right away. Dose is based on body weight and must be determined by your doctor. The starting dose is usually 3 to 5 milligrams mg per kilogram kg of body weight per day given as a single dose once a day. The first dose is started either 1 to 3 days before the transplant or on the day of the transplant. Your doctor may adjust your dose as needed. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.
The other issue you address are the respiratory complications of methotrexate. There is one very serious respiratory issue that can occur in patients taking methotrexate and this is called methotrexate pneumonitis. I warn my patients that if they develop cough, shortness of breath or fever-to stop methotrexate and be seen. Even thought many of my patients have a primary care doctor, I want to know when they are sick so they can be treated appropriately. I typically recommend that my patients who develop a cough on methotrexate be seen and get a chest xray. While methotrexate pneumonitis can be a very serious medical problem, it is fortunately not common and most patients who present with cough on this drug end up having a viral bronchitis and less commonly pneumonia.
In 2000 then aged 49 I was diagnosed with chronic RA. I won't describe all the painful symptoms, medical visits, drug side effects, depression, lethargy, lack of sleep, etc. as they are all too familiar to anyone who suffers from RA. I suffered for five years thanks to the ill informed specialists I was seeing who simply said 'incurable' and keep taking the tablets and all the other pills to overcome the side effects of these tablets, oh and regular blood tests to make sure we are not destroying your liver. Bir K, Herzenberg AM, Carette S "Azathioprine induced acute interstitial nephritis as the cause of rapidly progressive renal failure in a patient with Wegener's granulomatosis. DavidNeto E, daFonseca JA, dePaula FJ, Nahas WC, Sabbaga E, Ianhez LE "The impact of azathioprine on chronic viral hepatitis in renal transplantation: A long-term, single-center, prospective study on azathioprine withdrawal. Krishnan K, Adams P, Silveira S, Sheldon S, Dabich L "Therapy-related acute myeloid leukaemia following immunosuppression with azathioprine for polymyositis. Lemley DE, Delacy LM, Seeff LB, Ishak KG, Nashel DJ "Azathioprine induced hepatic veno-occlusive disease in rheumatoid arthritis. Well, it was great for over a year until I could no longer afford to eat this way and since I re-introduced breads and sometimes pasta into my diet my inflammation and pain had come back with a vengeance! Snow JL, Gibson LE "A pharmacogenetic basis for the safe and effective use of azathioprine and other thiopurine drugs in dermatologic patients. The use of the Truven Health products is at your sole risk. These products are provided "AS IS" and "as available" for use, without warranties of any kind, either express or implied. Truven Health and Drugs. Once you have any health problems fully treated, the next step is usually testing. Your doctor may refer you to a neuropsychologist, speech pathologist, or occupational therapist. Durezol is usually given 4 times per day for 2 weeks. After the first 2 weeks, your dose may be decreased to 2 times per day for 1 week or longer. Follow your doctor's instructions. Wilkinson AH, Smith JL, Hunsicker LG, et al "Increased frequency of posttransplant lymphomas in patients treated with cyclosporine, azathioprine, and prednisone. Cerner Multum, Inc. "UK Summary of Product Characteristics. Why am I going to Rheumatology now to give me my results? The weakness from myositis can lead to falls and make it difficult to get up from a chair or after a fall. Therapeutic response occurs after several weeks of therapy, usually 6 to 8 weeks. Patients not improved after 12 weeks can be considered refractory. Tage-Jensen U, Schlichting P, Thomsen HF, et al "Malignancies following long-term azathioprine treatment in chronic liver disease.
Wegener's granulomatosis experienced rapid progression of renal failure within 10 days of starting azathioprine for vasculitis. The increased risk of cancer may be more pronounced when azathioprine is used concomitantly with other immunosuppressive agents. Renal transplant patients may have a higher risk of developing lymphoproliferative disorders, lymphomas, and leukemia, as well as some solid tumors while receiving azathioprine. Floyd A, Pedersen L, Lauge Nielsen G, Thorlacius-Ussing O, Toft Sorensen H "Risk of acute pancreatitis in users of azathioprine: a population-based case-control study. If you will be taking this medicine for a long time, it is very important that your doctor check you at regular visits for any problems or unwanted effects that may be caused by this medicine. Blood tests may be needed to check for unwanted effects. Dosage reduction or alternative therapy may be required in patients with reduced thiopurine S-methyltransferase TPMT activity. Agarwal SK, Mittal D, Tiwari SC, Dash SC, Saxena S, Saxena R, Mehta SN "Azathioprine-induced pure red blood cell aplasia in a renal transplant recipient. flutamide
Shahnaz S, Choksi MT, Tan IJ "Bilateral cytomegalovirus retinitis in a patient with systemic lupus erythematosus and end-stage renal disease. The book's title is: A Doctor's Proven New Home Cure for Arthritis. I think it was HUGE back then for a medical professional to buck traditional pharmaceuticals and suggest that our diets are the real culprits. Dose adjustments may be required; however, no specific guidelines have been suggested. Mercaptopurine 6-MP in the treatment of inflammatory bowel disease IBD: a population-based study in Olmsted County, Minnesota. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist. To hear Dr. Gail Darlington speaking on BBC Radio 4 The Food Programme about Diet and Arthritis - it is 30 minutes well spent to listen to the whole show.
Nossent JC, Swaak AJ "Pancytopenia in systemic lupus erythematosus related to azathioprine. Take azathioprine with a full glass of water. RA symptoms through diet. My dad has done the same thing, though it was about 30 years ago. My blood ANA levels have previously been negative. Guillaume P, Grandjean E, Male PJ "Azathioprine-associated acute pancreatitis in the course of chronic active hepatitis. Benari Z, Mehta A, Lennard L, Burroughs AK "Azathioprine-induced myelosuppression due to thiopurine methyltransferase deficiency in a patient with autoimmune hepatitis. Another reason to eat well is that Crohn's can make it harder for your body to absorb the it needs. walmart price combivent otc
Now I do and now it makes perfect sense that my triggers and cycles of pain and inflammation are due to the processed carbs I have eaten! Patel AA, Swerlick RA, McCall CO "Azathioprine in dermatology: the past, the present, and the future. Bakker RC, Hollander AA, Mallat MJ, Bruijn JA, Paul LC, De Fijter JW "Conversion from cyclosporine to azathioprine at three months reduces the incidence of chronic allograft nephropathy. Use the missed dose as soon as you remember. Skip the missed dose if it is almost time for your next scheduled dose. Do not use extra medicine to make up the missed dose. What happens if I overdose? But the symptoms of viral infection may go away days or weeks before myositis symptoms begin. Major GA, Moore PG "Profound circulatory collapse due to azathioprine.
Azathioprine is used to prevent your body from rejecting a transplanted kidney. It is also used to treat symptoms of rheumatoid arthritis. Lower doses may be required; however, no specific guidelines have been suggested. Dodd HJ, Tatnall FM, Sarkany I "Fast atrial fibrillation induced by treatment of psoriasis with azathioprine. What should I discuss with my healthcare provider before taking azathioprine Imuran? Store at room temperature away from moisture, heat, and light. Keep the bottle tightly closed when not in use. What happens if I miss a dose? The amount of medicine that you take depends on the strength of the medicine. Also, the number of doses you take each day, the time allowed between doses, and the length of time you take the medicine depend on the medical problem for which you are using the medicine. Use with caution. The effects may be increased because of slower removal of the medicine from the body. El-Azhary RA, Brunner KL, Gibson LE "Sweet syndrome as a manifestation of azathioprine hypersensitivity. There have been reports of fungal, protozoal, viral, and uncommon bacterial infections, some of which have been fatal, in patients who are receiving azathioprine. Kerstens PJSM, Stolk JN, Deabreu RA, Lambooy LHJ, Vandeputte LBA, Boerbooms AAMT "Azathioprine-related bone marrow toxicity and low activities of purine enzymes in patients with rheumatoid arthritis. If you need surgery, tell the surgeon ahead of time that you are using azathioprine. You may need to stop using the medicine for a short time. Do not touch the tip of the eye dropper or place it directly on your eye. A contaminated dropper can infect your eye, which could lead to serious vision problems. pharmacy astelin
You should not stop using Durezol suddenly. Follow your doctor's instructions about tapering your dose. There are many causes of muscle weakness and pain more common than myositis, and testing for myositis is not a straightforward process. For these reasons, the process of diagnosing myositis can be long. You should not take this medicine if you are allergic to azathioprine, or if you are pregnant unless the benefits of treating you outweigh any risks posed by taking azathioprine. Azathioprine should be permanently withdrawn after occurrence of hypersensitivity reactions. While taking azathioprine, you may have a higher risk of developing skin cancer. Talk to your doctor about this risk and what skin symptoms to watch for. Use only the number of drops your doctor has prescribed. If you use more than one drop, wait about 5 minutes between drops. If test results show that MS is to blame for spotty memory or poor mental focus, you may want to try rehab to sharpen your thinking. You wrote in your post above that you "can assure anyone reading this that diet is not a "cure" for actual chronic RA, which is not curable. Ask your doctor to give you updates on any promising results. At least three cases of atrial fibrillation have been reported one case involving a patient with ulcerative colitis although causality is unknown. A 52-year-old male with steroid-dependent ulcerative colitis experienced atrial fibrillation coincident with azathioprine therapy. The drug had been started 3 years earlier, but discontinued after a few months because the patient reported palpitations, lipothymia, nausea, and vomiting. Upon a rechallenge with 50 mg of azathioprine, the patient showed general malaise, nausea, and vomiting. An ECG showed atrial fibrillation, and the patient reported that the symptoms were similar to those experienced previously.
Skin lesions resolved 30 days after drug withdrawal. Anstey A, Lennard L, Mayou SC, Kirby JD "Pancytopenia related to azathioprine-an enzyme deficiency caused by a common genetic polymorphism: a review. Appropriate studies have not been performed on the relationship of age to the effects of azathioprine in the pediatric population. Safety and efficacy have not been established. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use Durezol only for the indication prescribed. RA entered my life forever. Duran S, Apte M, Alarcon GS, et al. "Features associated with, and the impact of, hemolytic anemia in patients with systemic lupus erythematosus: LX, results from a multiethnic cohort. Drugs for rheumatoid arthritis. Additionally, TRUVEN HEALTH MAKES NO REPRESENTATION OR WARRANTIES AS TO THE OPINIONS OR OTHER SERVICE OR DATA YOU MAY ACCESS, DOWNLOAD OR USE AS A RESULT OF USE OF THE THOMSON REUTERS HEALTHCARE PRODUCTS. ALL IMPLIED WARRANTIES OF MERCHANTABILITY AND FITNESS FOR A PARTICULAR PURPOSE OR USE ARE HEREBY EXCLUDED. Truven Health does not assume any responsibility or risk for your use of the Truven Health products. What should I discuss with my healthcare provider before taking Imuran azathioprine? Some of the side effects that can occur with azathioprine may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. To me, anything that results in less pain, less swelling, improved mobility, and just overall health benefits is awesome, and if diet does it for anyone, more power to them. And if medicine and whatever is needed to control pain is what works, more power to these persons too. Regardless, from what I have read, we all want our lives back, so go get it back and cure yourselves in any way you can. Food and Drug Administration. WebMD does not endorse any specific product, service or treatment. If you need to have surgery, tell the surgeon ahead of time that you are using azathioprine. You may need to stop using the medicine for a short time. Post-transplant lymphoma and hepatosplenic T-cell lymphoma HSTCL has been reported in patients with inflammatory bowel disease. You may not be able to continue taking other arthritis medications together with azathioprine. Follow your doctor's dosing instructions very carefully. Duttera MJ, Carolla RL, Gallelli JF, et al "Hematuria and crystalluria after high-dose 6-mercaptopurine administration. dexamethasone
If you take this medicine more than once daily and you miss a dose, take the medicine as soon as you remember. If it is almost time for the next dose, take both doses together, then go back to your regular dosing schedule. Therapeutic response occurs after several weeks of treatment, usually 6 to 8; an adequate trial should be a minimum of 12 weeks. Patients not improved after 12 weeks can be considered refractory. IMURAN may be continued long-term in patients with clinical response, but patients should be monitored carefully, and gradual dosage reduction should be attempted to reduce risk of toxicities. The principal and potentially serious toxic effects of azathioprine the active ingredient contained in Imuran are hematologic and gastrointestinal. Risk of secondary infection and malignancy is also significant. Frequency and severity of side effects depend on dose and duration of azathioprine as well as on underlying disease or concomitant therapies. Hematologic toxicities and neoplasia were reported more often in renal homograft recipients than in patients using azathioprine for rheumatoid arthritis. Your food choices can have a big impact on how well you feel. There isn't a specific "Crohn's eating plan. Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed. Azathioprine lowers your body's immune system. The immune system helps your body fight infections. The immune system can also fight or "reject" a transplanted organ such as a liver or kidney. This is because the immune system treats the new organ as an invader. How should I use Durezol? Other side effects not listed may also occur in some patients. If you notice any other effects, check with your healthcare professional. RA since 1994. My PCP and Rheumy have been asking for me to consider permanent disability for the past 3 years. Due to medical conditions that resulted in several operations over the past 2 years I applied for SSD in March 2011 and was approved in May 2011. Yes I feel guilty about being on SSD because I do have good days and think I should still be working and I go out and do to much and everything comes down on me and I realize the right decision was made and I thank my doctors for insisting I should be on disability. Anyone out there with RA who's doctors are recomending they be on disability, you should not feel guilty. The bad days seem to still outnumber the good ones, do yourself and your family a justifiable service and listen to your doctors and take there recomendations and apply. There are SSDI examiners who will make you contest there decisions but generally if it is justified you will recieve your SSDI. Remember SSDI is not an entitlement, it is an insurance policy you and your employer paid for in taxes deducted from your pay check. Do Not Feel Guilty, anyone that makes you feel guilty about SSDI are ones who would abuse the system if they could. Luckily I have a wonderful spouse, she has been so supportive and caring that no matter what I could do for her it would never be enough to repay her love and understanding. Food and Drug Administration. WebMD does not endorse any specific product, service, or treatment. Joshua Korzenik, MD. He is director of the Crohn's and Center at Massachusetts General Hospital. Data not available; approximately 45% of an azathioprine dose is removed by hemodialysis. Burger DC, Florin TH "Hepatosplenic T-cell lymphoma following infliximab therapy for Crohn's disease. Avoid contact sports or other situations where bruising or injury could occur. Store at room temperature away from moisture, heat, and light. Diet and Arthritis' by Gail Darlington and Linda Gamlin I was determined to get off medication and stick to the recommended elimination diet and food reintroduction program. Read all the other books and most contain some good info and a lot of misguided info.
CMV retinitis coincident with azathioprine therapy. It is theorized that immunosuppressive therapy may have a role in the development of CMV retinitis in this population. The patient responded to discontinuation of azathioprine, lowering of the corticosteroid dose, and systemic administration of ganciclovir. Azathioprine can lower blood cells that help your body fight infections. Your blood may need to be tested often. Avoid being near people who are sick or have infections. Avoid activities that may increase your risk of bleeding injury. Tell your doctor at once if you develop signs of infection. Crohn's is a complicated disease, and the treatments are always changing. Your best bet is to get treated by an experienced gastroenterologist. My diet restrictions also include: no gluten wheat, oat and barley and their products no dairy, no white sugar, no roasted nuts fresh are okay and are in fact essential, as they provide more easily digestible protein and essential oils. Once I am pain free I will start eating dairy and gluten products again, and see if the pain comes back. For now I'm eating lots of whole grain rice, quinoa, walnuts, almonds, the permitted vegetables and home-grown sprouted lentils and mung beans. The sprouts are good for all sorts of ailments, as they contain protein, vitamins, minerals and all sorts of enzymes that promote healthy cell growth and healing. Your doctor may prescribe two separate bottles of this medicine, one to use in each eye. This is to keep from passing infection from one eye to the other. Be sure to mark each bottle for the right or left eye, and use the eye drops from that bottle only in that eye. Within a couple of weeks there was noticeable improvement in terms of reduced swelling and pain, within a few months my mobility had improved and joints were only occasionally painful and after about 9 months of sticking with it I woke up one sunny day to find that even the morning stiffness feet like planks of wood had completely vanished. AMAZING! This medicine may cause blurred vision and may impair your thinking or reactions. Be careful if you drive or do anything that requires you to be alert and able to see clearly. Cytoxan chlorambucil Leukeran melphalan Alkeran. Imuran as early as three months after renal transplantation. It is not known whether Durezol will harm an unborn baby. Tell your doctor if you are pregnant. You should be seeing a lot of your gastroenterologist. Go to all your scheduled appointments. It will keep your treatment on track and let your doctor make changes to your medication, if needed. God Bless you all. MS needs constant care or can't live on his or her own. If this becomes an issue, discuss your options with your doctor and family. A social worker or also can help explore options for care. Can Medicine Help? buy cheap betapace otc
Barreto SG, Tiong L, Williams R "Drug-induced acute pancreatitis in a cohort of 328 patients. A single-centre experience from Australia. Elijovisch F, Krakoff LR "Captopril associated granulocytopenia in hypertension after renal transplantation. The optimum duration of maintenance IMURAN has not been determined. IMURAN can be discontinued abruptly, but delayed effects are possible. Amaro R, Neff GW, Karnam US, Tzakis AG, Raskin JB "Acquired hyperplastic gastric polyps in solid organ transplant patients. Duvoux C, Kracht M, Lang P, Vernant JP, Zafrani ES, Dhumeaux D "Hyperplasie nodulaire regenerative du foie associee a la prise d'azathioprine. Some people using azathioprine have developed a rare fast-growing type of lymphoma cancer. This condition affects the liver, spleen, and bone marrow, and it can be fatal. This has occurred mainly in teenagers and young adults using azathioprine or similar medicines to treat Crohn's disease or ulcerative colitis. Sterneck M, Wiesner R, Ascher N, et al "Azathioprine hepatotoxicity after liver transplantation. Millard PR, Herbertson BM, Evans DB, Calne RY "Azathioprine hepatotoxicity in renal transplantation. Tilt your head back slightly and pull down your lower eyelid to create a small pocket. Hold the dropper above the eye with the tip down. Look up and away from the dropper and squeeze out a drop. Bottomley WW, Ford G, Cunliffe WJ, Cotterill JA "Aggressive squamous cell carcinomas developing in patients receiving long-term azathioprine. Azathioprine can pass into breast milk and may harm a nursing baby. You should not breast-feed while you are using azathioprine. There is a new test available whereby you doctor can determine the level of methotrexate in your blood. If my patients have a low level of methotrexate in the tissue and they are not doing well, I will typically switch them to weekly subcutaneous methotrexate injections to enhance absorption and hopefully efficacy. Azathioprine may cause a serious viral infection of the brain that can lead to disability or death. Call your doctor right away if you have any change in your mental state, decreased vision, or problems with speech or walking. These symptoms may start gradually and get worse quickly.
Fonclare AL, Khosrotehrani K, Aractingi S, Duriez P, Cosnes J, Beaugerie L "Erythema Nodosum-like Eruption as a Manifestation of Azathioprine Hypersensitivity in Patients With Inflammatory Bowel Disease. Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. 'Multum' is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. We are here with you and all sending good thoughts out to each other. I wish you the best, and you can consider this a Cyber Hug if you need one. BUT even if you dont try the diet, just READ the book! Dx with HIV in the mid eighties, and through the past two and a half decades, he has outlasted probably a million or more persons who have passed away from that horrible virus, and his treatments consist of vitamins, massage, acupuncture and diet. She manages to treat herself with herbal medicine, acupuncture, meditation, and much more I'm sure. There are infinite possibilities out there for all of us RA'ers as well as people who suffer from cancer, diabetes, heart disease, and any other prevalent disease in our society today. I am a huge believer that diet has just as much to do with disease as anything else, along with stress, suppressed anger, allergens, pollutants, ozone, and also that RA existed long before there was a name for it, or people knew what it was. I happen to believe that many of us have the propensity to come down with a number of diseases, and certain things "trigger" our bodies to start attacking itself. It's a natural thing for our bodies to do, us auto-immuners just can't stop it from doing it in a bad way. Follow all directions on your prescription label. Your doctor may occasionally change your dose to make sure you get the best results. Do not take this medicine in larger or smaller amounts or for longer than recommended. Join a Crohn's disease support group, where you can share experiences with people who've gone through the same challenges. To learn about support groups in your area, contact the Crohn's and Foundation of America. RA pain in my knees. For the past five months - since the beginning of this recent flair-up I have suffered from mild RA in my hips and knees for the past 40 years, but until now have managed to get rid of it within a few weeks, following slight changes in my diet and the stabilizing of the weather - I have been doing several things concurrently, which have alieviated some of the pain, but I want to get rid of it altogether. Alopecia has been reported in patients on azathioprine monotherapy or in combination with other immunosuppressants. This side effect may resolve spontaneously despite ongoing therapy. What other drugs will affect azathioprine Imuran? Urine may also turn a dark brown or red color. omur.info ranolazine
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Gradual dose reduction is recommended to reduce the risk of toxicities. If you suspect impaired thinking, talk with your neurologist or family doctor. Fuzzy thinking can have many causes. Azathioprine can lower blood cells that help your body fight infections. This can make it easier for you to bleed from an injury or get sick from being around others who are ill. Your blood may need to be tested often. Visit your doctor regularly. RA now. I applaud your finding the diet info. Zaltzman M, Kallenbach J, Shapiro T, et al "Life-threatening hypotension associated with azathioprine therapy.
Product Information. Imuran azathioprine. Cunningham T, Barraclough D, Muirden K "Azathioprine-induced shock. Sometimes your best ally in preventing flare-ups from is common sense. Avoid these key errors to keep at bay. Not okay by me. I cannot convince him to give me the results.
Ironic is that my mom is a two-insulin diabetic for years but I am not although I am reactive hypoglycemic. When i have that under control I also do better with pain as well. People look at your diet cause my ancestors are Native American plains Indians-who spend most of their time eating buffalo and no processed carbs. Now on reservations they have high incidences of diabetes because they eat more processed carbs. Seems to me that your food ancestry is of significance here as well. I fully believe that body type is a big factor in how we process foods and how we are evolved for specialization. My fiancee is Irish and is a true hypoglycemic. He has to eat lots of carbs and proteins in small meals all day to be healthy and keep at a weight of 165. He is 6 ft tall and feels at his best when he can keep at that weight but he burns off food like it was rocket fuel-really fast. Keeping the weight on is his biggest problem. I fully believe that metabolism is closely related to auto-immunological diseases.
Katska DA, Saul SH, Jorkasky D, Sigal H, Reynolds JC, Soloway RD "Azathioprine and hepatic venocclusive disease in renal transplant patients. Now, the question. My pulmonologist is bouncing me to rheumatology to tell me my lung biopsy results. Azathioprine-induced hypotension is independent of dose and may accompany signs and symptoms of hypersensitivity. Hypotension may be profound, although it is usually responsive to intravenous fluids and, if hypersensitivity is suspected, corticosteroids. Not all side effects for Imuran may be reported. You should always consult a doctor or healthcare professional for medical advice.